We studied effects of spatial and temporal features of visual stimulation on saccadic eye movement’s parameters in young
and older healthy volunteers and patients with early stages of Parkinson’s disease. Three stimulation paradigms were
used: no delay, overlap and gap. The visual targets were located to the right and left, up and down from the central
stimulus. Our findings have demonstrated that the temporal characteristics of stimulation had significant effects on
saccadic latency and duration in all the groups of participants. The factor of spatial location of visual targets had
less pronounced influence on latency and duration of saccades than the temporal factor. Spatial asymmetry of saccadic
parameters was associated with individual properties of the participants, age and disease factors. Patients with
Parkinson’s disease had longer saccadic latencies, produced gap effect with smaller magnitude and performed much more
multistep saccades then age-matched controls. The degree of saccadic abnormalities demonstrated by parkinsonian patients
depended both on stimulation paradigm and on spatial location of visual targets.
Key words:
saccades, gap effect, asymmetry, Parkinson’s disease
Cite:
Ratmanova P. O., Litvinova A. S., Bogdanov R. R., Napalkov D. A., Polyanskii V. B.
Vliyanie vremennykh i prostranstvennykh kharakteristik stimulov na parametry sakkadicheskikh dvizhenii glaz v norme i pri bolezni parkinsona
[Effects of temporal and spatial features of visual stimulation on saccades in normal controls and parkinsonian patients].
Sensornye sistemy [Sensory systems].
2016.
V. 30(1).
P. 29-41 (in Russian).
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