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Volume 32 #2

Contents

  1. Tinnitus – contemporary knowledge about its origin, electrophysiological correlates and treatment
  2. Eye optics and retinal topography in the nutria (Myocastor coypus)
  3. Quantitative study of Poggendorff illusion in school children with normal binocular vision and with strabismus
  4. The method of canine odor visualization
  5. Precopulatory mechanisms of reproductive isolation between two chromosomal forms of striped hamsters Cricetulus barabensis sensu lato (Rodentia, Cricetinae)
  6. Discrimination of sound signals with rippled spectra in on- and low-frequency noise: contribution of compressive nonlinearity and confounding issues
  7. The equivalent frequency-tuned filter form for discrimination of spectral pattern of sound signals: Contribution of the lateral suppression and harmonics

Tinnitus – contemporary knowledge about its origin, electrophysiological correlates and treatment

© 2018 N.G. Bibikov

JSC N.N. Andreyev Acoustical Institute 117036 Moscow, Shvernik st., 4

Received 10 Aug 2017

In this review we discuss contemporary literature that deals with problems of phantom sensation of sound (tinnitus). Various hypotheses concerning its origin, different physiological manifestations, as well as possible methods of treatment, are considered. We concentrated on the works dealing with the modeling of tinnitus on laboratory animals and on the studies of the role of peculiarities of auditory neurons impulse activity in this syndrome. Changes in the parameters of background firing in the dorsal cochlear nucleus and in the principal nucleus of the inferior colliculus are the most obvious correlates of this syndrome in laboratory animals. These changes are manifested in the increase in average frequency, in the enhancement of neuronal cross-correlation and in the appearance of burst activity. Results obtained in cortical structures, thalamus, and basal nuclei remain less clear. The most probable cause of tinnitus is a disturbance in the balance of excitation and inhibition in the process of plastic rearrangements of the auditory pathway. Physiological experiments in humans reveal a diversity of tinnitus genesis and its manifestations in cortical responses. We discuss plastic reorganization of receptive fields by prolonged presentation of specially selected stimuli as a promising method of treating tonal and narrowband tinnitus.

Key words: tinnitus, ringing in the ears, auditory neurons, spontaneous activity

DOI: 10.7868/S0235009218020014

Cite: Bibikov N. G. Tinnitus – sovremennye znaniya o ego proiskhozhdenii, elektrofiziologicheskikh korrelyatakh i o lechenii [Tinnitus – contemporary knowledge about its origin, electrophysiological correlates and treatment]. Sensornye sistemy [Sensory systems]. 2018. V. 32(2). P. 109-123 (in Russian). doi: 10.7868/S0235009218020014

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