• 1990 (Том 4)
  • 1989 (Том 3)
  • 1988 (Том 2)
  • 1987 (Том 1)

ТИННИТУС – СОВРЕМЕННЫЕ ЗНАНИЯ О ЕГО ПРОИСХОЖДЕНИИ, ЭЛЕКТРОФИЗИОЛОГИЧЕСКИХ КОРРЕЛЯТАХ И О ЛЕЧЕНИИ

© 2018 г. Н. Г. Бибиков

АО Акустический институт им. акад. Н.Н. Андреева 117036 Москва, ул. Шверника, 4
nbibikov1@yandex.ru

Поступила в редакцию 10.08.2017 г.

Приведен обзор основных современных работ, связанных с проблемами фантомного ощущения звука – тиннитуса. Рассмотрены различные гипотезы, касающиеся его происхождения, различных физиологических проявлений, а также возможных методов лечения. Основное внимание уделено рассмотрению работ, связанных с моделированием тиннитуса на лабораторных животных, и исследованию особенностей импульсной активности нейронов слухового пути при проявлении данного синдрома. Изменения параметров фоновой импульсации в дорсальном кохлеарном ядре и в заднем двухолмии являются наиболее четким коррелятом наличия его у лабораторных животных. Эти изменения сводятся к возрастанию средней частоты, усилению взаимной корреляции и появлению пачковой активности. Данные, касающиеся корковых структур, таламуса и базальных ядер, остаются менее определенными. Наиболее вероятной причиной тиннитуса является нарушение баланса возбуждения и торможения в процессе пластических перестроек слухового пути. Физиологические эксперименты на людях выявляют разнообразие причин его происхождения и его проявлений в корковых ответах. Среди методик борьбы с тиннитусом перспективным представляется достижение пластической перестройки рецептивных полей путем длительного предъявления специально подобранных стимулов.

Ключевые слова: тиннитус, звон в ушах, нейроны слухового пути, спонтанная активность

DOI: 10.7868/S0235009218020014

Цитирование для раздела "Список литературы": Бибиков Н. Г. Тиннитус – современные знания о его происхождении, электрофизиологических коррелятах и о лечении. Сенсорные системы. 2018. Т. 32. № 2. С. 109-123. doi: 10.7868/S0235009218020014
Цитирование для раздела "References": Bibikov N. G. Tinnitus – sovremennye znaniya o ego proiskhozhdenii, elektrofiziologicheskikh korrelyatakh i o lechenii [Tinnitus – contemporary knowledge about its origin, electrophysiological correlates and treatment]. Sensornye sistemy [Sensory systems]. 2018. V. 32(2). P. 109-123 (in Russian). doi: 10.7868/S0235009218020014

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