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Volume 30 #3

Contents

  1. The structural-functional organization of mammalian auditory cortex as the basis of acoustic information cortical processing. The structural organization
  2. Allocation of the characteristic features of in low-frequency envelope of the tone by the neurons in the midbrain auditory center of the frog
  3. Discrimination of sound signals with rippled spectra in the noises of different spectral compositions
  4. Temporary threshold shifts in naïve and experienced belugas
  5. The role of simpatic-epinephrine system in the changes of electrical activity of the brain hemisphere cortex and hypothalamus under vibration exposure
  6. Cyclic polypeptide PP-14 modulates the voltage sensitivity of slow sodium channels
  7. Training optimal Viola–Jones detectors using greedy algorithms for selecting control parameters with intermediate validation on each level
  8. Abnormal band in the circular dichroism spectrum of DNA cholesteric liquid-crystalline dispersions – an analytical criteriom for detection of coloured biologically active compounds

Abnormal band in the circular dichroism spectrum of DNA cholesteric liquid-crystalline dispersions – an analytical criteriom for detection of coloured biologically active compounds

© 2016 Yu. M. Evdokimov, S. V. Semenov, S. G. Skuridin, V. I. Salyanov, P. N. Sol’ev, V. T. Valuev-Elliston, F. V. Vereshchagin, D. P. Chulkov, O. N. Kompanets

Engelgardt Institute of Molecular Biology, RAS Vavilov st. 32, 119991 Moscow
National Research Centre “Kurchatov Institute”, Kurchatov sq. 1, 123182 Moscow
Institute of Spectroscopy, RAS Fizicheskaya st. 5, Troitsk, 142190 Moscow

Received 30 Mar 2016

The сircular dichroism (CD) spectra of the cholesteric liquid-crystalline dispersions (CLCD) formed by double-stranded DNA molecules at various parameters of these particles (size, cholesteric pitch, etc.) have been calculated. Besides, the CD spectra in the case of colored antibiotics (analytes) interaction with DNA molecules in the content of dispersion particles were calculated. It was shown that an abnormal band in the CD spectra represents, by itself, a simple, convenient criterion, which allows one not only detect the presence of analytes in solutions being analyzed, but evaluate their concentration. It opens a possibility for the using CLCD particles as the biosensing units for analytical systems dealing with detection of colored antibiotics.

Key words: cholesteric liquid-crystalline dispersions, circular dichroism, abnormal optical activity, “quasinematic” layers, antibiotics

Cite: Yu. M. Evdokimov, Semenov S. V., Skuridin S. G., Salyanov V. I., Sol’ev P. N., Valuev-Elliston V. T., Vereshchagin F. V., Chulkov D. P., Kompanets O. N. Anomalnaya polosa v spektre krugovogo dikhroizma kholestericheskikh zhidkokristallicheskikh dispersii dnk – analiticheskii kriterii dlya obnaruzheniya okrashennykh biologicheski aktivnykh soedinenii [Abnormal band in the circular dichroism spectrum of dna cholesteric liquid-crystalline dispersions – an analytical criteriom for detection of coloured biologically active compounds]. Sensornye sistemy [Sensory systems]. 2016. V. 30(3). P. 249-259 (in Russian).

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