Volume 36 #1

Contents

1. An overview of the visual acuity assessment. 2. Theoretical and clinical requirements to the optotypes and chart designs
2. Assessment of peripheral visual acuity in various conditions of testing
3. The expression and function of components of signaling cascades of taste, olfactory, and phototransduction in mammalian pancreas beta-cells
4. Recognition of projectively transformed planar figures. XVI The octet of projectively stable vertices of the oval and new methods for its reference description using the octet
5. Heteroscedasticity correction to improve tomographic reconstruction with an algebraic approach

The taste, olfactory, and visual systems are responsible for the detection and recognition of diverse physical and chemical stimuli of environment. Proteins involved in sensory transduction pathways are expressed in highly specific manner in taste cells, olfactory neurons, retinal cones and rods. However, the ectopic expression of the components of the transduction cascades mediating sensory reception were also found in betacells of mammalian pancreatic islets that synthesize, store, and release the hormone insulin. The functional role of the proteins involved in sensory transduction in the physiology of beta-cells remains unclear. A growing body of evidence indicates that in beta-cells, they may participate in the regulation of glucose stimulated insulin release and insulin production. Here, we provide a review of what is known about ectopic expression of the components of the transduction cascades of sensory reception in pancreas beta-cells as well as in the insulinoma cell lines, which retain glucose stimulated insulin secretion as isolated islets.

Key words: beta-cells, islets of Langerhans, insulin secretion, ectopic expression, signaling cascade, olfactory transduction, taste transduction, phototransduction

DOI: 10.31857/S0235009222010048

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