Volume 35 #1

Contents

1. Ommochromes of the Compound Eye of Insects: Antiglycation Activity
2. Visual neurons of fish tectum opticum, their extracellular spike activity and search for their adequate stimulation
3. Downregulation of cockroach UV-sensitive visual pigment decreases masking effect of short wavelength illumination
4. Frequency-time features of eye movement when using the video-oculographic interface in ergatic system control problems
5. The use of vibrational signals of insects to develop safe methods for pest control
6. General ensemble method for multi-view clustering
7. Improvement of a line segment detector based on a neural network by adding engineering features
8. Recognition of projectively transformed planar figures. XV. Methods for searching for axes and centers of ovals with symmetries, using a set of dual pairs of cevian triads
9. Hardware independence and accuracy of neural network denoising of images depending on training set size

Ommochromes – screening and antioxidant organelles of the compound eye of invertebrates perform the function of light filtration, light absorption and antioxidant protection. In the present work, it was found for the first time that ommochromes exhibit antiglycation activity in vitro. Ommochromes were obtained from the eyes of three different insect families: Strationyidae, Sphingidae, and Acrididae. It was shown that all the studied ommochromes inhibited the reaction of formation of fluorescent products of serum albumin modification in the presence of high fructose concentrations (fructosylation). Ommochromes from the eyes of the black soldier fly (Hermetia illucens) were the most effective inhibitors of the fructosylation process. Ommochromes oxidized with hydrogen peroxide did not exhibit an inhibitory effect on the glycation process. The results obtained are of interest both for understanding the biological role of ommochromes in invertebrates, in particular for elucidating their effect on the oxidative modification of proteins of retinular and pigment cells of ommatidium, and for creating pharmacological preparations based on them for the treatment and prevention of pathologies associated with the development of metabolic syndrome.

Key words: ommochromes, insects, glycation, fructosylation

DOI: 10.31857/S0235009221010030

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