Characteristics of morphological development of the extreme retinal periphery near ora serrata

© 2018 I. G. Panova, R. A. Poltavtseva, G. I. Rozhkova

N.K. Koltsov Institute of Developmental Biology, Russian Academy of Sciences, 119334 Moscow, ul. Vavilova 26, Russia
V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Public Health of Russia, 117997 Moscow, ul. Akademika Oparina 4, Russia
Institute for Information Transmission Problems (Kharkevich Institute), Russian Academy of Sciences, 127051 Moscow, Bolshoi Karetny lane, 19, Russia

Received 09 Apr 2018

The histological data presented in this paper characterize the early stages of development (5.5–20 weeks) of the extreme visual retinal periphery in human (pars optica retinae) near ora serrata where retina undergoes transformsation into blind tunic under ciliar body (pars caeca retinae) lacking photosensitivity. This area attracted attention of investigators due to a cone-enriched rim (CER) whose origin and functions had been most often discussed in psychophysical but not morphological literature. The analysis of our data and the data published by other investigators allows suggestion that different hypotheses about the role of CER could have relation to different zones of the extreme periphery. The “morphological” hypothesis implying that CER cells could migrate from the peripheral to the central area and could serve as a source of material for the rest of the retina might be related to the area of the extreme periphery occupying more anterior position than CER and containing immature not differentiated cells. As for the “psychophysical” hypotheses on the participation of CER in the mechanisms of color constancy and locomotion control, these hypotheses might only be related to the more posterior part of the extreme periphery containing mature cells and similar in structure to the main part of the retina.

Key words: human eye, prenatal development, ora serrata, extreme retinal periphery, cone-enriched rim

DOI: 10.1134/S0235009218040091

Cite: Panova I. G., Poltavtseva R. A., Rozhkova G. I.. Morfologicheskaya kharakteristika razvitiya krainei periferii setchatki v oblasti ora serrata [Characteristics of morphological development of the extreme retinal periphery near ora serrata]. Sensornye sistemy [Sensory systems]. 2018. V. 32(4). P. 302-309 (in Russian). doi: 10.1134/S0235009218040091


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